Genetic diversity assessments in the century of genome science

TitleGenetic diversity assessments in the century of genome science
Publication TypeJournal Article
Year of Publication2010
AuthorsYahara T, Donoghue MJ, Zardoya R, Faith DP, Cracraft J
JournalCurrent Opinion In Environmental Sustainability
Volume2
Pagination43 - 49
ISSN18773435
KeywordsENVIRONMENTAL SCIENCES
Abstract

Genetic elements determine phenotypes of organisms by interacting with environments. Despite genetic diversity within and between species being the fundamental basis of biological diversity, its contribution has been long neglected in biodiversity studies. This situation is rapidly changing as quantification of genetic diversity, from intraspecific up to the ecosystem level, has become more accessible owing to the development of next-generation sequencing technologies (NGSTs). Whole-genome sequencing techniques provide two specific approaches for accessing genetic diversity at large scales: metagenomics (environmental genomics) and EST (Expressed Sequence Tag) comparisons. The former has been applied successfully in the profiling of different microbial biomes, and it is particularly interesting in understanding their ecosystem structure and function. The latter is particularly useful in the studies of adaptation and the assessment of functional traits. Unquestionably, advances in the

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